Hexahydrocannabinol, or HHC for short, is a new star in the world of cannabinoids. It was discovered in 1944. HHC is naturally occurring in the hemp plant and is developing into an exciting cannabis trend.
HHC belongs to the cannabinoid family. Over 100 of them have been found in hemp seeds and plants. Its unique structure makes it special. HHC is resistant to oxidation, UV light and temperature fluctuations.
The rise of HHC as a cannabis trend is impressive. Since December 2022, HHC has been found in at least 13 EU countries. In Germany, HHC has become particularly popular. Späti stores offer HHC pens, which are well received by customers.
The most important findings
- HHC is a naturally occurring cannabinoid, discovered in 1944
- It is characterized by resistance to external influences
- HHC has been detected in at least 13 EU countries
- The popularity of HHC products is growing in Germany
- The legal situation of HHC is still unclear in many countries
What is HHC
Hexahydrocannabinol, or HHC for short, is an exciting cannabinoid. It has a special chemical structure. HHC is similar to THC, but it is completely saturated.
These properties make HHC unique. It differs from other cannabinoids.
The chemical structure of hexahydrocannabinol
The chemical structure of HHC is C21H32O2. It has a molecular structure with a mass of 316.485 g-mol-1. There are two isomers: 9β-HHC and 9α-HHC.
The 9β isomer binds more strongly to cannabinoid receptor 1 and is about ten times more active than the 9α isomer.
Natural occurrence in the hemp plant
HHC occurs naturally in the hemp plant, but only in small quantities. This makes extraction difficult and expensive. In 2020, a group of researchers found HHC in Cannabis sativa.
It was previously discovered in 1972. It is a decomposition product of THC in hemp.
Discovery by Roger Adams
The story of HHC begins in 1947, when it was discovered by the chemist Roger Adams. Adams’ work was an important step in cannabinoid research.
Despite the early discovery, HHC only became known now. This is mainly due to TikTok.
Production and mode of action of HHC
HHC is mainly produced in laboratories. It is only found in small quantities in the hemp plant. The process was first described in 1940 and has been further developed since then.
Semi-synthetic laboratory production
The production of HHC begins with CBD as the starting material. Chemical processes are used to convert CBD into HHC. This process is similar to the development of Delta-8-THC, which was launched on the US market in 2019.

Interaction with the endocannabinoid system
HHC has a similar effect to THC on the endocannabinoid system. It binds to cannabinoid receptors and influences physical and mental functions. The effect of HHC is described as comparable to cannabis, but with less intensity.
Differences to THC and CBD
Compared to THC, HHC has a weaker psychoactive effect. HHC vs THC: While THC falls under the Narcotics Act, HHC is currently unregulated. CBD, on the other hand, has no intoxicating effect. HHC is therefore positioned between these two well-known cannabinoids.
- HHC: Weaker psychoactive effects than THC
- THC: Strong psychoactive effect, regulated by law
- CBD: No intoxicating effect, legally available
Despite the increasing use of HHC products, experts warn of potential health risks. This is due to a lack of long-term studies and potential impurities from the manufacturing process.
Legal framework in Germany
The legal situation in Germany regarding HHC has changed significantly. On June 27, 2024, hexahydrocannabinol was included in the New Psychoactive Substances Act (NpSG). This is a major turning point in cannabis legislation and has a major impact on HHC legality.
Before the ban, HHC was in a gray area. It was not listed in the Narcotics Act (BtMG) and could be traded freely. Now the sale and manufacture is illegal. Possession remains permitted as long as the products were purchased before the deadline.

The ban applies not only to HHC, but also to THCP and 1D-LSD. This shows how quickly the laws for new psychoactive substances are changing. For the hemp industry, this means re-planning their business models and possibly suffering economic losses.
| Substance | Legal status | Prohibition date |
|---|---|---|
| HHC | Illegal (sale/manufacture) | 27.06.2024 |
| THCP | Illegal | 27.06.2024 |
| 1D-LSD | Illegal | 27.06.2024 |
| 10-OH-HHC | Legal | – |
The effects of the ban on research and development in the cannabis sector are still unclear. It remains to be seen how the legal situation in Germany will develop. And what consequences this could have for cannabis legislation as a whole.
Health risks and side effects
The effect of HHC on health has not yet been fully researched. However, some risks and side effects are already known. These deserve our attention.
Undesirable side effects
HHC can have similar effects to THC. Common symptoms include:
- Dry mouth
- Reddened eyes
- Dizziness and confusion
- Palpitations
- Nausea
- Headaches
- insomnia
- anxiety
There are also reports of psychotic states with incorrect dosage. Some people report hallucinations.
Heavy metal residues from production
Another risk is heavy metal residues in HHC products. The lack of quality controls increases this risk. Sometimes even banned substances are sprayed onto HHC flowers.
Detectability in drug tests
HHC can be detected in drug tests. This is a particular problem for working people or drivers. Detectability depends on the test method and the metabolism.
Experts such as Prof. Oliver Pogarell are seeing an increase in patients in addiction clinics. These patients have consumed HHC. Long-term studies are lacking, but psychological problems such as anxiety and depression are being discussed as possible consequences.
Conclusion
HHC, an exciting cannabinoid, is at the center of cannabis research. It was discovered in the 1940s. The future of HHC promises exciting developments, but also challenges.
Research into cannabinoids is making progress. HHC has interesting properties. It is more stable than THC and less susceptible to degradation by light or heat.
Its effect is similar to that of THC, but less intense. Nevertheless, comprehensive studies on safety and long-term effects are lacking.
The legal situation of HHC is unclear. In Germany, synthetic HHC currently falls into a gray area. Austria and Finland regard it as a new psychoactive substance. Clear regulations are important for the future of HHC.
Research must focus intensively on HHC. There are risks such as heavy metal residues and undesirable side effects. More detailed studies are needed to ensure safety and to exploit the potential of HHC.
FAQ
What exactly is HHC?
HHC stands for hexahydrocannabinol. It was discovered in 1944 by Roger Adams. It is a molecule that is similar to THC but has unique properties. HHC occurs naturally in the hemp plant, but is usually produced in the laboratory.
How does the effect of HHC differ from THC and CBD?
HHC has a similar effect to THC, but weaker. Compared to CBD, HHC has stronger effects. Its effect is a mixture of relaxation and mild euphoria.
Is HHC legal in Germany?
No, HHC is not legal in Germany. It was recently banned. Laws are changing rapidly to keep up with new cannabinoids.
What are the health risks associated with the use of HHC?
The risks of HHC are not yet fully known. Side effects can include anxiety and nausea. Heavy metal residues from production are another risk. Consumption may be detectable in drug tests.
How is HHC produced?
HHC is produced in a laboratory process. First, CBD is extracted from hemp. Then it is converted into HHC through hydrogenation.
Can HHC be detected in drug tests?
Yes, HHC can be detected in drug tests. Although it is different from THC, some tests may have difficulties. Its use can have legal or professional consequences.
What future does HHC have in cannabis research?
Despite its prohibition in Germany, HHC is an exciting field of research. Its unique properties could provide new insights. The future depends on research, regulations and possible applications.